Publications
A 3D Human Airway Model Enables Prediction of Respiratory Toxicity of Inhaled Drugs In Vitro
Toxicological Sciences (Mar. 2018)
Balogh Sivars, Kinga; Sivars, Ulf; Hornberg, Ellinor; Zhang, Hui; Brändén, Lena; Bonfante, Rosy; Huang, Song; Constant, Samuel; Robinson, Ian; Betts, Catherine J; Åberg, Per M
Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium
British Journal of Pharmacology (Jan. 2018)
Brookes, Daniel W; Coates, Matthew; Allen, Heather; Daly, Leah; Constant, Samuel; Huang, Song; Hows, Mark; Davis, Amanda; Cass, Lindsey; Ayrton, John; Knowles, Ian; Strong, Pete; Rapeport, Garth; Ito, Kazuhiro
Human lung epithelial cell cultures for analysis of inhaled toxicants: Lessons learned and future directions
Toxicology in Vitro (Mar. 2018)
Hiemstra, Pieter S.; Grootaers, Gwendolynn; van der Does, Anne M.; Krul, Cyrille A. M.; Kooter, Ingeborg M.
Combining MucilAir™ and Vitrocell® Powder Chamber for the In Vitro Evaluation of Nasal Ointments in the Context of Aerosolized Pollen
Pharmaceutics (Jun. 2018)
Metz, Julia; Knoth, Katharina; Groß, Henrik; Lehr, Claus-Michael; Stäbler, Carolin; Bock, Udo; Hittinger, Marius
Application of a direct aerosol exposure system for the assessment of biological effects of cigarette smoke and novel tobacco product vapor on human bronchial epithelial cultures
Regulatory Toxicology and Pharmacology (Jul. 2018)
Ishikawa, Shinkichi; Matsumura, Kazushi; Kitamura, Nobumasa; Ishimori, Kanae; Takanami, Yuichiro; Ito, Shigeaki
Thyme extract increases mucociliary-beating frequency in primary cell lines from chronic obstructive pulmonary disease patients
Biomedicine & Pharmacotherapy (Sep. 2018)
Nabissi, Massimo; Marinelli, Oliviero; Morelli, Maria Beatrice; Nicotra, Giovanna; Iannarelli, Romilde; Amantini, Consuelo; Santoni, Giorgio; Maggi, Filippo
Antiviral drug screening by assessing epithelial functions and innate immune responses in human 3D airway epithelium model
Antiviral Research (Aug. 2018)
Boda, Bernadett; Benaoudia, Sacha; Huang, Song; Bonfante, Rosy; Wiszniewski, Ludovic; Tseligka, Eirini D.; Tapparel, Caroline; Constant, Samuel
Rhinosectan® spray (containing xyloglucan) on the ciliary function of the nasal respiratory epithelium; results of an in vitro study
Allergy, Asthma & Clinical Immunology (Oct. 2018)
Piqué, Núria; De Servi, Barbara
A Case Study for the Comparison of In Vitro Data Across Multiple Aerosol Exposure Studies with Extrapolation to Human Dose
Applied In Vitro Toxicology (Apr. 2018)
Thorne, David; Bishop, Emma; Haswell, Linsey; Gaça, Marianna
A practical approach to assess inhalation toxicity of metal oxide nanoparticles in vitro
Journal of Applied Toxicology (Jan. 2018)
Dankers, Anita C. A.; Kuper, C. Frieke; Boumeester, Anja J.; Fabriek, Babs O.; Kooter, Ingeborg M.; Gröllers-Mulderij, Mariska; Tromp, Peter; Nelissen, Inge; Zondervan-Van Den Beuken, Esther K.; Vandebriel, Rob J.