Publications
human rhinovirusnasal epitheliaresveratrolinflammatory mediators
Resveratrol inhibits rhinovirus replication and expression of inflammatory mediators in nasal epithelia
Antiviral Research
Paola Mastromarino, Daniela Capobianco, Federica Cannata, Chiara Nardis, Elena Mattia, Alessandra De Leo, Rossella Restignoli, Antonio Francioso, Luciana Mosca
Mitochondrial Ca 2+ -dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa -driven inflammatory response in cystic fibrosis
Nature Communications
Alessandro Rimessi, Valentino Bezzerri, Simone Patergnani, Saverio Marchi, Giulio Cabrini, Paolo Pinton
Human organotypic nasal epithelial tissue culture as an in vitro model to evaluate effects of cigarette smoke of a candidate Modified Risk Tobacco Product: the Tobacco Heating System 2.2
C. Mathis, M. Cabanski, S. Frenzel, D. Kuehn, Shoaib Majeed, Céline Merg, A. Elamin, E. Guedj, Rémi H. J. Dulize, Dariusz Peric, Keyur P. Trivedi, A. Benyagoub, Y. Xiang, F. Martin, P. Leroy, N. Ivanov, M. Peitsch, J. Hoeng
atmosphères mono ou multi-polluantscontrôle analytiqueinterface air-liquideair-liquid interfacehuman airway reconstituted epithelium614.4atmosphere mono or multi-pollutantépithéliumrepeated exposureepithélium respiratoire reconstituéexpositions répétéescomposés organiques volatilsépidémiologieanalytical control
Modèles in vitro adaptés à l’étude de la relation entre la pollution de l’air intérieur et la santé respiratoire, application aux Composés Organiques Volatils (COV)
Gaëlle Bardet, Nathalie Seta
cutaneous respirationprincipal component analysissensory perceptiongenomicscytotoxic t cellschemical compoundssupport vector machinesbiomarkers
Prediction of Chemical Respiratory Sensitizers Using GARD, a Novel In Vitro Assay Based on a Genomic Biomarker Signature
PLOS ONE
Andy Forreryd, Henrik Johansson, Ann-Sofie Albrekt, Carl A. K. Borrebaeck, Malin Lindstedt
Airway Epithelial Cell Integrity Protects from Cytotoxicity of Pseudomonas aeruginosa Quorum-Sensing Signals
American Journal of Respiratory Cell and Molecular Biology
Davide Losa, Thilo Köhler, Marc Bacchetta, Joanna Bou Saab, Maud Frieden, Christian van Delden, Marc Chanson
15-lipoxygenaseasthmaeoxin c15-heteglutathione transferaseairway epithelial cells
On the biosynthesis of 15-HETE and eoxin C4 by human airway epithelial cells
Prostaglandins & Other Lipid Mediators
Åsa Brunnström, Ylva Tryselius, Stina Feltenmark, Erik Andersson, Helene Leksell, Anna James, Bengt Mannervik, Barbro Dahlén, Hans-Erik Claesson
preclinicaltumour microenvironmentlung cancer3d model
Antitumour efficacy of the selumetinib and trametinib MEK inhibitors in a combined human airway–tumour–stroma lung cancer model
Journal of Biotechnology
Christophe Mas, Bernadett Boda, Mireille CaulFuty, Song Huang, Ludovic Wiszniewski, Samuel Constant
neurodegenerationparkinson's diseasehost defenselysosomal storage diseaseautophagyalzheimer's diseasemucussecretory lysosomeinflammation
A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca2+ release from acidic Ca2+ stores
Cell Calcium
Giorgio Fois, Nina Hobi, Edward Felder, Andreas Ziegler, Pika Miklavc, Paul Walther, Peter Radermacher, Thomas Haller, Paul Dietl
Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies: IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells
American Journal of Physiology - Lung Cellular and Molecular Physiology
Danielle O'Connell, Belaid Bouazza, Blerina Kokalari, Yassine Amrani, Alaa Khatib, John David Ganther, Omar Tliba