Publications
A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca2+ release from acidic Ca2+ stores
Cell Calcium (Dec. 2015)
Fois, Giorgio; Hobi, Nina; Felder, Edward; Ziegler, Andreas; Miklavc, Pika; Walther, Paul; Radermacher, Peter; Haller, Thomas; Dietl, Paul
Resveratrol inhibits rhinovirus replication and expression of inflammatory mediators in nasal epithelia
Antiviral Research (Nov. 2015)
Mastromarino, Paola; Capobianco, Daniela; Cannata, Federica; Nardis, Chiara; Mattia, Elena; De Leo, Alessandra; Restignoli, Rossella; Francioso, Antonio; Mosca, Luciana
Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis
Nature Communications (Feb. 2015)
Rimessi, Alessandro; Bezzerri, Valentino; Patergnani, Simone; Marchi, Saverio; Cabrini, Giulio; Pinton, Paolo
Targeted omics analyses, and metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term cultures of reconstituted human airway epithelia
Toxicology in Vitro (Mar. 2015)
Baxter, Andrew; Thain, Simon; Banerjee, Anisha; Haswell, Linsey; Parmar, Aleesha; Phillips, Gary; Minet, Emmanuel
Neutrophil proteases alter the interleukin-22-receptor-dependent lung antimicrobial defence
European Respiratory Journal (Aug. 2015)
Guillon, Antoine; Jouan, Youenn; Brea, Deborah; Gueugnon, Fabien; Dalloneau, Emilie; Baranek, Thomas; Henry, Clémence; Morello, Eric; Renauld, Jean-Christophe; Pichavant, Muriel; Gosset, Philippe; Courty, Yves; Diot, Patrice; Si-Tahar, Mustapha
D prostanoid receptor 2 (chemoattractant receptor–homologous molecule expressed on TH2 cells) protein expression in asthmatic patients and its effects on bronchial epithelial cells
Journal of Allergy and Clinical Immunology (Feb. 2015)
Stinson, Sally E.; Amrani, Yassine; Brightling, Christopher E.
Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts
Toxicological Sciences (Sep. 2015)
Iskandar, Anita R.; Xiang, Yang; Frentzel, Stefan; Talikka, Marja; Leroy, Patrice; Kuehn, Diana; Guedj, Emmanuel; Martin, Florian; Mathis, Carole; Ivanov, Nikolai V.; Peitsch, Manuel C.; Hoeng, Julia
Antitumour efficacy of the selumetinib and trametinib MEK inhibitors in a combined human airway–tumour–stroma lung cancer model
Journal of Biotechnology (Jul. 2015)
Mas, Christophe; Boda, Bernadett; CaulFuty, Mireille; Huang, Song; Wiszniewski, Ludovic; Constant, Samuel
Aspergillus Biofilm In Vitro and In Vivo
Microbial Biofilms (Jan. 2015)
Beauvais, Anne; Latgé, Jean-Paul
On the biosynthesis of 15-HETE and eoxin C4 by human airway epithelial cells
Prostaglandins & Other Lipid Mediators (Sep. 2015)
Brunnström, Åsa; Tryselius, Ylva; Feltenmark, Stina; Andersson, Erik; Leksell, Helene; James, Anna; Mannervik, Bengt; Dahlén, Barbro; Claesson, Hans-Erik