Publications
Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach
Toxicology Research (Nov. 2017)
Iskandar, Anita R.; Martinez, Yannick; Martin, Florian; Schlage, Walter K.; Leroy, Patrice; Sewer, Alain; Torres, Laura Ortega; Majeed, Shoaib; Merg, Celine; Trivedi, Keyur; Guedj, Emmanuel; Frentzel, Stefan; Mathis, Carole; Ivanov, Nikolai V.; Peitsch, Manuel C.; Hoeng, Julia
ATP is stored in lamellar bodies to activate vesicular P2X4 in an autocrine fashion upon exocytosis
Journal of General Physiology (Dec. 2017)
Fois, Giorgio; Winkelmann, Veronika Eva; Bareis, Lara; Staudenmaier, Laura; Hecht, Elena; Ziller, Charlotte; Ehinger, Konstantin; Schymeinsky, Jürgen; Kranz, Christine; Frick, Manfred
Preclinical characterization of the inhaled small molecule respiratory syncytial virus L-protein polymerase inhibitor, PC786
Antimicrobial Agents and Chemotherapy (Aug. 2017)
Coates, Matthew; Brookes, Daniel; Kim, Young-In; Allen, Heather; Fordyce, Euan; Meals, Elizabeth; Colley, Thomas; Ciana, Claire-Lise; Parra, Guillaume; Sherbukhin, Vladimir; Stockwell, Jennifer; Thomas, Jennifer; Hunt, S.; Anderson-Dring, Lauren; Onions, Stuart; Cass, Lindsey; Murray, Peter; Ito, Kazuhiro; Strong, Pete; Rapeport, Garth
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing
Toxicology in Vitro (Jun. 2017)
Hamm, Jon; Sullivan, Kristie; Clippinger, Amy J.; Strickland, Judy; Bell, Shannon; Bhhatarai, Barun; Blaauboer, Bas; Casey, Warren; Dorman, David; Forsby, Anna; Garcia-Reyero, Natàlia; Gehen, Sean; Graepel, Rabea; Hotchkiss, Jon; Lowit, Anna; Matheson, Joanna; Reaves, Elissa; Scarano, Louis; Sprankle, Catherine; Tunkel, Jay; Wilson, Dan; Xia, Menghang; Zhu, Hao; Allen, David
Human bocavirus: Current knowledge and future challenges
World Journal of Gastroenterology (Oct. 2016)
Guido, Marcello; Tumolo, Maria Rosaria; Verri, Tiziano; Romano, Alessandro; Serio, Francesca; De Giorgi, Mattia; De Donno, Antonella; Bagordo, Francesco; Zizza, Antonella
3.5 - Cell-based in vitro models for pulmonary permeability studies
Concepts and Models for Drug Permeability Studies (Jan. 2016)
Andrade, Fernanda; Albuquerque, João; Nascimento, Ana Vanessa
A framework for in vitro systems toxicology assessment of e-liquids
Toxicology Mechanisms and Methods (Jul. 2016)
Iskandar, Anita R.; Gonzalez-Suarez, Ignacio; Majeed, Shoaib; Marescotti, Diego; Sewer, Alain; Xiang, Yang; Leroy, Patrice; Guedj, Emmanuel; Mathis, Carole; Schaller, Jean-Pierre; Vanscheeuwijck, Patrick; Frentzel, Stefan; Martin, Florian; Ivanov, Nikolai V.; Peitsch, Manuel C.; Hoeng, Julia
Cellular Effects in an In Vitro Human 3D Cellular Airway Model and A549/BEAS-2B In Vitro Cell Cultures Following Air Exposure to Cerium Oxide Particles at an Air–Liquid Interface
Applied In Vitro Toxicology (Mar. 2016)
Kooter, Ingeborg M.; Gröllers-Mulderij, Mariska; Steenhof, Maaike; Duistermaat, Evert; van Acker, Frederique A.A.; Staal, Yvonne C.M.; Tromp, Peter C.; Schoen, Eric; Kuper, C. Frieke; van Someren, Eugene
Influence of the Surfactant Tyloxapol on Mucociliary Clearance in Human Respiratory Cystic Fibrosis Cells
Pharmacology (Mar. 2016)
Beubler, Eckhard; Fischer, Rainald; Untersteiner, Gerald; Strohmaier, Wolfgang
New use for an old drug: COX-independent anti-inflammatory effects of sulindac in models of cystic fibrosis
British Journal of Pharmacology (Jan. 2016)
Rocca, Jérémy; Manin, Sylvie; Hulin, Anne; Aissat, Abdel; Verbecq-Morlot, Wilfried; Prulière-Escabasse, Virginie; Wohlhuter-Haddad, Adeline; Epaud, Ralph; Fanen, Pascale; Tarze, Agathe