Publications
Divergent responses to SARS-CoV-2 infection in bronchial epithelium with pre-existing respiratory diseases
iScience (Mar. 2025)
Oliva, Justine; Ruffin, Manon; Calmel, Claire; Gibeaud, Aurélien; Pizzorno, Andrés; Gaudin, Clémence; Chardonnet, Solenne; Bastos, Viviane de Almeida; Rosa-Calatrava, Manuel; Soulé, Antoine; Emad, Amin; Rousseau, Simon; Corvol, Harriet; Terrier, Olivier; Guillot, Loïc
Fifteen day repeat air: liquid Interface air-only exposures can cause respiratory epithelium injury in MucilAir™ nasal respiratory epithelial cells that parallels chemically induced cytotoxicity
Toxicology Mechanisms and Methods (Jan. 2025)
Recio, Leslie; Samuel, Raymond; Elmore, Susan A.; Scaglione, Jamie
S11-01 Assessing the potential toxicity of chemicals using human respiratory cell-based <i>in vitro</i> systems
Toxicology Letters (Sep. 2025)
Roldan, N.; Stucki, A. O.; Sharma, M.; Verstraelen, S.; Jacobs, A.; Hollanders, K.; Van Laer, J.; Remy, S.; Frijns, E.; Clippinger, A. J.
Real-world outdoor air exposure effects in a model of the human airway epithelium – A comparison of healthy and asthmatic individuals using a mobile laboratory setting
Ecotoxicology and Environmental Safety (Jan. 2025)
Rossner, Pavel; Libalova, Helena; Cervena, Tereza; Sima, Michal; Simova, Zuzana; Vrbova, Kristyna; Ambroz, Antonin; Novakova, Zuzana; Elzeinova, Fatima; Vimrova, Anezka; Dittrich, Lubos; Vojtisek, Michal; Pechout, Martin; Vojtisek-Lom, Michal
Flagellin-mediated TLR5 activation enhances innate immune responses in healthy and diseased human airway epithelium
nan (Nov. 2025)
Li, Xing; Cayet, Delphine; Zeroual, Yasmine; Sanjuán-García, Itziar; Bonnefond, Amélie; Derhourhi, Mehdi; Caul-Futy, Mireille; Caul-Futy, Christine; Poll, Tom van der; Carnoy, Christophe; Baldry, Mara; Constant, Samuel; Sirard, Jean-Claude
Assessing the toxicity of traffic-derived air pollution using a primary human air-liquid interface airway <i>in vitro</i> model
Environmental Research (Nov. 2025)
Bredeck, Gerrit; Wahle, Tina; Kämpfer, Angela A. M.; Dobner, Jochen; Boere, A. John F.; Fokkens, Paul; Duistermaat, Evert; Spannbrucker, Tim; Rossi, Andrea; Cassee, Flemming R.; Schins, Roel P. F.
Evaluation of a non-animal toolbox informed by adverse outcome pathways for human inhalation safety
Frontiers in Toxicology (Feb. 2025)
de Ávila, Renato Ivan; Müller, Iris; Barlow, Hugh; Middleton, Alistair Mark; Theiventhran, Mathura; Basili, Danilo; Bowden, Anthony M.; Saib, Ouarda; Engi, Patrik; Pietrenko, Tymoteusz; Wallace, Joanne; Boda, Bernadett; Constant, Samuel; Behrsing, Holger Peter; Patel, Vivek; Baltazar, Maria Teresa
An in vitro model of the epithelial airway reveals a key function for EHF in lung homeostasis and disease
Disease Models & Mechanisms (Jul. 2025)
Pinte, Laetitia; Vila-Gonzalez, Marta; Williams, Eleanor C.; Causa, Erika; Fradique, Ricardo; Pauzaite, Tekle; Passemar, Charlotte; Becca, Silvia; Gribben, Christopher; Ye, Shiqi; Al-Thani, Maha; Bachinger, Fabian; Roos, Floris J. M.; Nathan, James A.; Mohorianu, Irina; Floto, Andres; Cicuta, Pietro; Vallier, Ludovic
Senolytic therapy reduces inflammation in epithelial cells from COPD patients and in smoke-exposure mice
Frontiers in Medicine (Apr. 2025)
Baker, Jonathan R.; Daly, Leah; Hassibi, Shyreen; Kimura, Genki; Nishimoto, Yuki; Kizawa, Yasuo; Ito, Kazuhiro
LP-35 Development of an Optimized <i>in vitro</i> model for Range Finding in Acute Inhalation Toxicity: An Alternative to MucilAir™
Toxicology Letters (Sep. 2025)
Park, J. Y.; Bang, I. J.; Han, Y.; Kim, G. E.; Lim, J. E.; Yu, J. H.; Yoo, J.; Kim, H. R.