Publications
Cilia dynamics create a dynamic barrier to penetration of the periciliary layer in human airway epithelia
Proceedings of the National Academy of Sciences (Jul. 2025)
Causa, Erika; Das, Debasish; Feriani, Luigi; Kotar, Jurij; Cicuta, Pietro
A Proof-of-Concept for Safety Evaluation of Inhalation Exposure to Known Respiratory Irritants Using In Vitro and In Silico Methods
Toxics (Jan. 2025)
Sadekar, Nikaeta; Behrsing, Holger Peter; Hansen, Tanja; Patel, Vivek; Paulo, Hazel; Rae, Alex; Ritter, Detlef; Schwarz, Katharina; Api, Anne Marie
P29-08 Development of a novel <i>in vitro</i> platform for the detection of profibrotic compounds based on primary human alveolar epithelium
Toxicology Letters (Sep. 2025)
Pira, E.; Arib, G.; Boda, B.; Huang, S.; Constant, S.
Two- and Three-Dimensional Culture Systems: Respiratory In Vitro Tissue Models for Chemical Screening and Risk-Based Decision Making
Pharmaceuticals (Jan. 2025)
Wallace, Joanne; McElroy, Mary C.; Klausner, Mitchell; Corley, Richard; Ayehunie, Seyoum
A human relevant in vitro alveolar epithelial barrier model to assess inhaled pollutant hazard
Scientific Reports (Nov. 2025)
Bateman, Joshua W. P.; Meldrum, Kirsty; Mitchell, Sarah M.; Vogel, Ulla; Clift, Martin J. D.
Acute Exposure to Aerosolized Nanoplastics Modulates Redox-Linked Immune Responses in Human Airway Epithelium
Antioxidants (Mar. 2025)
Breidenbach, Joshua D.; French, Benjamin W.; Shrestha, Upasana; Adya, Zaneh K.; Wooten, R. Mark; Fribley, Andrew M.; Malhotra, Deepak; Haller, Steven T.; Kennedy, David J.
An ACE2-Fc decoy produced in glycoengineered plants neutralizes ancestral and newly emerging SARS-CoV-2 variants and demonstrates therapeutic efficacy in hamsters
Scientific Reports (Apr. 2025)
Föderl-Höbenreich, Esther; Izadi, Shiva; Hofacker, Lara; Kienzl, Nikolaus; Castilho, Alexandra; Strasser, Richard; Tarrés-Freixas, Ferran; Cantero, Guillermo; Roca, Núria; Pérez, Mònica; Lorca-Oró, Cristina; Usai, Carla; Segalés, Joaquim; Vergara-Alert, Júlia; Mach, Lukas; Zatloukal, Kurt
Quantitative characterisation of extracellular vesicles designed to decoy or compete with SARS-CoV-2 reveals differential mode of action across variants of concern and highlights the diversity of Omicron
Cell Communication and Signaling (Jul. 2025)
Schürz, Melanie; Pagani, Isabel; Klinglmayr, Eva; Melo Benirschke, Heloisa; Mayora Neto, Martin; Galietta, Luis J. V.; Venturini, Arianna; Pedemonte, Nicoletta; Capurro, Valeria; Laner-Plamberger, Sandra; Grabmer, Christoph; Emminger, Essi; Wolf, Martin; Steiner, Marianne; Kohlmetz, Cyrus; Mayr, Niklas; Paniushkina, Liliia; Schallmoser, Katharina; Strunk, Dirk; Brandstetter, Hans; Hintersteiner, Martin; Temperton, Nigel; Vicenzi, Elisa; Meisner-Kober, Nicole
Nanoscopy Reveals Heparan Sulfate Clusters as Docking Sites for SARS-CoV-2 Attachment and Entry
nan (Sep. 2025)
Han, Sue; Wang, Xin; Li, Tiansheng; Mohseni, Ammar; Kosik, Ivan; Chan, Chung Yu; López-Muñoz, Alberto Domingo; Matthias, Jessica; Suddaby, Reid; Wang, Zhixiong; Jin, Albert J.; Wurm, Christian A.; Yewdell, Jonathan W.; Wu, Ling-Gang
Dynamics of interactions between three major respiratory pathogens in reconstituted human epithelium
nan (Nov. 2025)
Gibeaud, Aurélien; Terra, Charles; Portier, Émilie; Lukas, Pascal; Gouellec, Audrey Le; Guedj, Jeremie; Graw, Frederik; Pizzorno, Andrés; Terrier, Olivier