Publications
Optimal preclinical models for human dose projection of SARS-CoV-2 small molecule direct-acting antivirals
nan (Sep. 2025)
Toselli, Francesca; Jacobs, Sofie; Scheers, Els; Jacobs, Tom; Doijen, Jordi; Hereijgers, Joyce; Keustermans, Ken; Aerts, Liese; van Heerden, Marjolein; Van Loock, Marnix; Mason, Stephen W.; Monshouwer, Mario; Van Damme, Ellen; Herschke, Florence
A pan-respiratory virus attachment inhibitor with high potency in human airway models and in vivo
Science Advances (Aug. 2025)
Mathez, Gregory; Silva, Paulo Jacob; Carlen, Vincent; Deloizy, Charlotte; Prompt, Clémentine; Hubart, Anaïs; Rocha-Pereira, Joana; Galloux, Marie; Le Goffic, Ronan; Stellacci, Francesco; Cagno, Valeria
Use of NAMs in a weight of evidence approach to evaluate the safety via the inhalation route of acetylated vetiver oil, in spray products
Regulatory Toxicology and Pharmacology (Nov. 2025)
Boisleve, Fanny; Vandecasteele, Hind Assaf; Baily, James; Czuchrowski, Kamil; Diop, Malik; Gadras, Catherine; Herbst, David; Hickey, Christina; Irizar, Amaia; Müller, Boris P.; Sadekar, Nikaeta; Sterchele, Paul; Vey, Matthias; Hewitt, Nicola J.
Structure-Guided Optimization and Functional Characterization of Small Molecule Antagonists Targeting CD28 Costimulation
nan (Oct. 2025)
Upadhyay, Saurabh; Nada, Hossam; Cho, Sungwoo; Gabr, Moustafa T.
The effects of e-cigarette aerosol components on the morphology and function of the conducting portion of the respiratory system: a narrative literature review
Pomeranian Journal of Life Sciences (Jun. 2024)
Szumilas, Paweł; Szumilas, Kamila; Wilk, Aleksandra; Zawiślak, Alicja; Karakiewicz, Beata
Divergent trajectory of replication and intrinsic pathogenicity of SARS-CoV-2 Omicron post-BA.2/5 subvariants in the upper and lower respiratory tract
eBioMedicine (Jan. 2024)
Hu, Bingjie; Chan, Jasper Fuk-Woo; Liu, Yuanchen; Liu, Huan; Chen, Yan-Xia; Shuai, Huiping; Hu, Ye-Fan; Hartnoll, Madeline; Chen, Li; Xia, Yao; Hu, Jing-Chu; Yuen, Terrence Tsz-Tai; Yoon, Chaemin; Hou, Yuxin; Huang, Xiner; Chai, Yue; Zhu, Tianrenzheng; Shi, Jialu; Wang, Yang; He, Yixin; Cai, Jian-Piao; Zhou, Jie; Yuan, Shuofeng; Zhang, Jinxia; Huang, Jian-Dong; Yuen, Kwok-Yung; To, Kelvin Kai-Wang; Zhang, Bao-Zhong; Chu, Hin
The triple combination of Remdesivir (GS-441524), Molnupiravir and Ribavirin is highly efficient in inhibiting coronavirus replication in human nasal airway epithelial cell cultures and in a hamster infection model
Antiviral Research (Nov. 2024)
Do, Thuc Nguyen Dan; Abdelnabi, Rana; Boda, Bernadett; Constant, Samuel; Neyts, Johan; Jochmans, Dirk
Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection
Virology Journal (Apr. 2024)
Bondeelle, Louise; Salmona, Maud; Houdouin, Véronique; Diaz, Elise; Dutrieux, Jacques; Mercier-Delarue, Séverine; Constant, Samuel; Huang, Song; Bergeron, Anne; LeGoff, Jérôme
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters
Journal of Antimicrobial Chemotherapy (Jan. 2024)
Box, Helen J; Sharp, Joanne; Pennington, Shaun H; Kijak, Edyta; Tatham, Lee; Caygill, Claire H; Lopeman, Rose C; Jeffreys, Laura N; Herriott, Joanne; Neary, Megan; Valentijn, Anthony; Pertinez, Henry; Curley, Paul; Arshad, Usman; Rajoli, Rajith K R; Jochmans, Dirk; Vangeel, Laura; Neyts, Johan; Chatelain, Eric; Escudié, Fanny; Scandale, Ivan; Rannard, Steve; Stewart, James P; Biagini, Giancarlo A; Owen, Andrew
The antiviral potential of the antiandrogen enzalutamide and the viral-androgen signaling interplay in seasonal coronaviruses
Journal of Medical Virology (Jan. 2024)
Ogunjinmi, Oluwadamilola D.; Abdullahi, Tukur; Somji, Riaz-Ali; Bevan, Charlotte L.; Barclay, Wendy S.; Temperton, Nigel; Brooke, Greg N.; Giotis, Efstathios S.