Broad antiviral and anti-inflammatory efficacy of nafamostat against SARS-CoV-2 and seasonal coronaviruses in primary human bronchiolar epithelia
Nano Select
Brian F Niemeyer, Caitlin M Miller, Carmen Ledesma-Feliciano, James H Morrison, Rocio Jimenez-Valdes, Clarissa Clifton, Eric M Poeschla, Kambez H Benam
Air-liquid interface exposure of in vitro lung models: improvement and application to study inhalation toxicity of aircraft-related air pollutants
Ruiwen He
Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples
Scientific reports
Emmanuel Minet, Linsey E Haswell, Sarah Corke, Anisha Banerjee, Andrew Baxter, Ivan Verrastro, Francisco De Abreu e Lima, Tomasz Jaunky, Simone Santopietro, Damien Breheny, others
Evaluation of the Biological Effects of Novel Tobacco Product Vapor Using Two-or Three-Dimensional Culture Systems of Human Bronchial Epithelia
Applied In Vitro Toxicology
Sakura Mori, Kanae Ishimori, Ikuya Tanabe, Shinkichi Ishikawa
Increased transmission of SARS-CoV-2 lineage B. 1.1. 7 (VOC 2020212/01) is not accounted for by a replicative advantage in primary airway cells or antibody escape
Jonathan C Brown, Daniel H Goldhill, Jie Zhou, Thomas P Peacock, Rebecca Frise, Niluka Goonawardane, Laury Baillon, Ruthiran Kugathasan, Andreia Pinto, Paul F McKay, others
Long-term evolution of the epithelial cell secretome in preclinical 3D models of the human bronchial epithelium
Scientific reports
Daniel Sanchez-Guzman, Sonja Boland, Oliver Brookes, Claire Mc Cord, René Lai Kuen, Valentina Sirri, Armelle Baeza Squiban, Stéphanie Devineau
The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets
Nature Microbiology
Thomas P Peacock, Daniel H Goldhill, Jie Zhou, Laury Baillon, Rebecca Frise, Olivia C Swann, Ruthiran Kugathasan, Rebecca Penn, Jonathan C Brown, Raul Y Sanchez-David, others
Toxicity of stainless and mild steel particles generated from gas–metal arc welding in primary human small airway epithelial cells
Scientific reports
Andrea Cediel-Ulloa, Christina Isaxon, Axel Eriksson, Daniel Primetzhofer, Mauricio A Sortica, Lars Haag, Remco Derr, Giel Hendriks, Jakob Löndahl, Anders Gudmundsson, others
SLC6A14 Modulates Lung Disease Severity in Cystic Fibrosis and Affects mTOR Phosphorylation and Bronchial Epithelial Repair
Julia Mercier, Claire Calmel, Julie Mésinèle, Erika Sutanto, Fatiha Merabtene, Elisabeth Longchampt, Edouard Sage, Anthony Kicic, Pierre-Yves Boëlle, Harriet Corvol, others
Establishment of an in vitro test strategy for orally inhaled drug products
Julia Katharina Metz